Gene	Timepoints- on treatment	Duration	Follow-up post therapy	Notes
Low risk APL PML::RARA	Bone marrow MRD- post each cycle of treatment	Stop performing MRD once CRMRD		Recommended by both ELN and Dillon et al
High risk APL PML::RARA	Bone marrow MRD- post each cycle of treatment		BM MRD every 3 months for 2-3 years	Recommended by both ELN and Dillon et al ELN recommend 2 years

High risk APL: MRD positive at End of Treatment (EoT) and chemotherapy treated high risk APL (even when patient is MRD negative at EoT)

Note: PB MRD not recommended due to rapid kinetics of relapse