| Gene | Timepoints- on treatment | Additional tests | Follow-up post therapy | Notes |
| CBFB::MYH11 and RUNX1::RUNX1T1 | Bone marrow MRD- post cycle 2 and EoTÂ | BM 3 monthly for 2 years or PB 2 monthly for 2 years | ELN recommends PB MRD monitoring 4-6 weekly but guidance local guidance is 2 monthly with enhanced monitoring if rising MRD (see below) |
