| Gene | Timepoints- on treatment | Additional tests | Follow-up post therapy | Notes |
| NPM1 | NPM1 PB MRD after cycle 2 and BM for EoT or Pre transplant | Consider US FLT3 ITD (if available) | 4-6 weekly in PB of 3 monthly for 2 years | Recommended by ELN DAVID |
| FLT3 ITD | US FLT3 ITD in BM and EoT/ pre transplant | NMP1 must still be performed | Sample on BM | ELN DAVID recommends FLT3 (as well as NPM1 if available) |
NOTE: FLT3 ITD ultrasensitive assay (US) is not performed at HCDP Manchester and is not part of test directory. If requested by referring team- will incur an extra cost.