AML FLT3 ITD (NPM1 wt)

GeneTimepoints- on treatmentAdditional testsFollow-up post therapyNotes
FLT3 ITD
(Ultra sensitive assay)
Bone marrow MRD- post cycle 2 and pre-transplant (EoT)
NANATest not performed by HCDP Manchester (send away to Guy’s). Can be sent by user request.
Recommended by ELN DAVID working party
Flow MRDBone marrow Flow MRD- post each cycle and EoTNAFollow up on BM 3 monthly for 12 monthsCan be used as alternative if US FLT3 assay not available

Note 1: Bone marrow preferred to PB. Test not part of funded test directory so will incur extra fee to reporting centre.